Lan Yang Selected Research

phospholipase C epsilon

1/2020	Hypomethylation-Linked Activation of PLCE1 Impedes Autophagy and Promotes Tumorigenesis through MDM2-Mediated Ubiquitination and Destabilization of p53.
1/2016	Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.
4/2014	Heterozygote of PLCE1 rs2274223 increases susceptibility to human papillomavirus infection in patients with esophageal carcinoma among the Kazakh populations.
1/2014	Elevated expression patterns and tight correlation of the PLCE1 and NF-κB signaling in Kazakh patients with esophageal carcinoma.
12/2013	[Relationship between rs2274223 and rs3765524 polymorphisms of PLCE1 and risk of esophageal squamous cell carcinoma in a Kazakh Chinese population].
11/2013	Multiple polymorphisms within the PLCE1 are associated with esophageal cancer via promoting the gene expression in a Chinese Kazakh population.
10/2013	Overexpression of PLCE1 in Kazakh esophageal squamous cell carcinoma: implications in cancer metastasis and aggressiveness.

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Lan Yang Research Topics

Disease

94	Neoplasms (Cancer) 07/2022 - 01/2006
16	Neoplasm Metastasis (Metastasis) 01/2022 - 10/2015
15	Infections 06/2022 - 04/2005
15	Inflammation (Inflammations) 01/2022 - 01/2014
14	Carcinogenesis 01/2022 - 06/2009
14	Esophageal Squamous Cell Carcinoma 11/2020 - 12/2009
12	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 06/2022 - 11/2003
12	Hepatocellular Carcinoma (Hepatoma) 02/2022 - 10/2007
12	Lung Neoplasms (Lung Cancer) 07/2021 - 01/2006
11	Asthma (Bronchial Asthma) 01/2022 - 09/2012
9	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 12/2007
9	Breast Neoplasms (Breast Cancer) 01/2021 - 12/2011
8	Carcinoma (Carcinomatosis) 01/2022 - 01/2006
8	Esophageal Neoplasms (Esophageal Cancer) 04/2021 - 01/2014
7	Hypoxia (Hypoxemia) 01/2022 - 11/2012
6	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022 - 12/2010
6	COVID-19 01/2022 - 01/2020
5	Pain (Aches) 06/2022 - 10/2011
5	Adenocarcinoma of Lung 01/2022 - 01/2017
5	Vascular Remodeling 01/2021 - 01/2017
5	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2019 - 09/2008
5	Papillomavirus Infections 01/2018 - 11/2012
4	Stroke (Strokes) 07/2022 - 12/2016
4	Rheumatoid Arthritis 02/2022 - 03/2017
4	Ischemia 01/2022 - 11/2004
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2015
4	Ischemic Stroke 10/2021 - 01/2017
4	Pneumonia (Pneumonitis) 11/2020 - 01/2006
4	Ovarian Neoplasms (Ovarian Cancer) 01/2018 - 12/2010
3	Brain Ischemia (Cerebral Ischemia) 07/2022 - 09/2017
3	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2022 - 01/2018
3	Osteoporosis 11/2021 - 01/2019
3	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2021 - 04/2018
3	Hyperglycemia 01/2021 - 09/2017
3	Type 2 Diabetes Mellitus (MODY) 01/2021 - 03/2010
3	Down Syndrome (Down's Syndrome) 02/2020 - 02/2014
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 12/2019
3	Disease Progression 12/2019 - 01/2016
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2019 - 01/2017
3	Pre-Eclampsia (Preeclampsia) 01/2019 - 01/2017
3	Glioma (Gliomas) 01/2019 - 03/2008
3	Pulmonary Hypertension 01/2018 - 03/2010
3	Lymphatic Metastasis 01/2018 - 10/2013
3	Pulmonary Arterial Hypertension 03/2017 - 03/2016
3	Human Influenza (Influenza) 01/2016 - 06/2011

Drug/Important Bio-Agent (IBA)

29	Proteins (Proteins, Gene)FDA Link 07/2022 - 04/2005
18	Biomarkers (Surrogate Marker)IBA 06/2022 - 01/2014
18	MicroRNAs (MicroRNA)IBA 01/2022 - 03/2012
11	EnzymesIBA 01/2022 - 04/2005
10	Pharmaceutical PreparationsIBA 01/2022 - 01/2018
9	CytokinesIBA 01/2021 - 01/2015
8	Messenger RNA (mRNA)IBA 01/2022 - 10/2013
8	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2006
7	Cisplatin (Platino)FDA LinkGeneric 09/2021 - 09/2010
7	phospholipase C epsilonIBA 01/2020 - 10/2013
6	RNA (Ribonucleic Acid)IBA 01/2022 - 03/2012
6	Circular RNAIBA 01/2022 - 01/2018
5	Long Noncoding RNAIBA 02/2022 - 01/2018
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 06/2009
5	Biological ProductsIBA 10/2021 - 10/2007
5	wogoninIBA 06/2021 - 09/2008
5	Dexamethasone (Maxidex)FDA LinkGeneric 12/2020 - 04/2009
5	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 03/2016
5	Oxygen (Dioxygen)IBA 09/2019 - 10/2011
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2019 - 04/2011
5	Peptides (Polypeptides)IBA 01/2019 - 01/2014
5	Small Interfering RNA (siRNA)IBA 10/2017 - 09/2010
4	Hematoxylin (Haematoxylon)IBA 01/2022 - 03/2017
4	Eosine Yellowish-(YS) (Eosin)IBA 01/2022 - 03/2017
4	Bronchodilator Agents (Bronchodilators)IBA 01/2022 - 12/2007
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 04/2009
4	PAR-2 ReceptorIBA 08/2021 - 10/2015
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 10/2017
4	Phosphotransferases (Kinase)IBA 01/2021 - 01/2017
4	Indicators and Reagents (Reagents)IBA 01/2021 - 12/2013
4	AntibodiesIBA 01/2020 - 01/2006
4	HLA-DRB1 Chains (HLA DRB1)IBA 10/2014 - 12/2009
3	AntioxidantsIBA 07/2022 - 01/2010
3	Thymidine PhosphorylaseIBA 02/2022 - 01/2019
3	LigandsIBA 10/2021 - 08/2012
3	Streptozocin (Streptozotocin)FDA Link 01/2021 - 09/2017
3	Peptide Hydrolases (Proteases)FDA Link 01/2021 - 01/2015
3	Particulate MatterIBA 11/2020 - 01/2018
3	Protein Kinases (Protein Kinase)IBA 11/2020 - 05/2016
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2020 - 01/2006
3	fibrin fragment D (D-dimer)IBA 01/2020 - 04/2005
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 06/2009
3	Docetaxel (Taxotere)FDA Link 01/2020 - 03/2015
3	Insulin (Novolin)FDA Link 12/2019 - 10/2017
3	Interleukin-8 (Interleukin 8)IBA 02/2019 - 09/2014
3	GoldIBA 01/2018 - 06/2011
3	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2018 - 03/2010
3	EpitopesIBA 01/2018 - 11/2012
3	Interleukin-6 (Interleukin 6)IBA 01/2017 - 01/2015
3	Interleukin-17 (Interleukin 17)IBA 01/2016 - 01/2015

Therapy/Procedure

39	Therapeutics 06/2022 - 12/2007
12	Drug Therapy (Chemotherapy) 04/2022 - 01/2011
6	Immunotherapy 12/2021 - 01/2019
5	Ligation 01/2022 - 10/2016
3	Neoadjuvant Therapy 01/2022 - 01/2018